Rett syndrome and genetic drift.

  title={Rett syndrome and genetic drift.},
  author={Erica M. B{\"u}hler and Naseem J. Malik and Mualla Alkan},
  journal={Brain & development},
  volume={21 3},
An X chromosome gene is assumed to be responsible for the cause of Rett syndrome (RS). However, new genealogical observations suggest involvement of autosomal recessive gene(s) as well, at least in familial cases. To account for these and other recent observations, the theoretical model presented in 1990 by the authors of this paper is applied to the… CONTINUE READING