Retroviral transfer of genes into canine hemopoietic progenitor cells in culture: a model for human gene therapy.

@article{Kwok1986RetroviralTO,
  title={Retroviral transfer of genes into canine hemopoietic progenitor cells in culture: a model for human gene therapy.},
  author={William W Kwok and Friedrich G. Schuening and Richard Stead and A Dusty Miller},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1986},
  volume={83 12},
  pages={4552-5}
}
Amphotropic retroviral vectors containing either a mutant dihydrofolate reductase gene (DHFR) or the bacterial neomycin phosphotransferase gene (neo) were used to infect canine hemopoietic cells. We report successful transfer and expression of the DHFR and neo genes in canine hemopoietic progenitor cells (colony-forming units, granulocyte/macrophage) as… CONTINUE READING