Retroviral recombination is nonrandom and sequence dependent.

@article{Wooley1998RetroviralRI,
  title={Retroviral recombination is nonrandom and sequence dependent.},
  author={Dawn P. Wooley and Lukas Bircher and R. A. Gordon Smith},
  journal={Virology},
  year={1998},
  volume={243 1},
  pages={
          229-34
        }
}
Sequence variation plays a significant role in the pathogenesis and persistence of retroviral infections and is a major obstacle in the development of vaccines as well as therapies against lethal diseases caused by retroviruses. Recombination is one means by which sequence variation is generated. However, the basic molecular mechanisms of recombination are not adequately understood. In the present study, a spleen necrosis virus (SNV) recombination system was used to ask whether a known hot spot… CONTINUE READING

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Recombinación del VIH-1 in vitro

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Reticuloendotheliosis viruses and derived vectors for human gene therapy.

  • Frontiers in bioscience : a journal and virtual library
  • 2003
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