Retroviral promoters in the human genome

  title={Retroviral promoters in the human genome},
  author={Andrew B. Conley and Jittima Piriyapongsa and I. King Jordan},
  volume={24 14},
MOTIVATION Endogenous retrovirus (ERV) elements have been shown to contribute promoter sequences that can initiate transcription of adjacent human genes. However, the extent to which retroviral sequences initiate transcription within the human genome is currently unknown. We analyzed genome sequence and high-throughput expression data to systematically evaluate the presence of retroviral promoters in the human genome. RESULTS We report the existence of 51,197 ERV-derived promoter sequences… 

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