Retroviral labeling of Schwann cells: in vitro characterization and in vivo transplantation to improve peripheral nerve regeneration.

@article{Mosahebi2001RetroviralLO,
  title={Retroviral labeling of Schwann cells: in vitro characterization and in vivo transplantation to improve peripheral nerve regeneration.},
  author={Afshin Mosahebi and Brian Woodward and Mikael Wiberg and Roland Martin and Giorgio Terenghi},
  journal={Glia},
  year={2001},
  volume={34 1},
  pages={8-17}
}
Transplantation of Schwann cells (SCs) is a promising treatment modality to improve neuronal regeneration. Identification of the transplanted cells is an important step when studying the development of this method. Genetic labeling is the most stable and reliable method of cell identification, but it is still unclear whether it has deleterious effect on SC characteristics. Our aim was to achieve a stable population of SCs transduced with the lacZ gene at a high frequency using a retroviral… CONTINUE READING

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