Retrotransposons influence the mouse transcriptome: implication for the divergence of genetic traits.

@article{Horie2007RetrotransposonsIT,
  title={Retrotransposons influence the mouse transcriptome: implication for the divergence of genetic traits.},
  author={Kyoji Horie and Ei-suke Saito and Vincent W Keng and Ryuji Ikeda and Hiroshi Ishihara and J. Takahashi Takeda},
  journal={Genetics},
  year={2007},
  volume={176 2},
  pages={815-27}
}
Massive accumulation of retrotransposons, comprising >40% of human and mouse genomes, is one of the major events in the evolution of the genome. However, most retrotransposons have lost retrotransposition competency, which makes studying their role in genome evolution elusive. Intracisternal A-particle (IAP) elements are long terminal repeat (LTR)-type mouse retrotransposons consisting of full-length and internally deleted types. Some are retrotransposition competent and their upregulated… CONTINUE READING

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