Retrospective safety analysis of atomoxetine in adult ADHD patients with or without comorbid alcohol abuse and dependence.

@article{Adler2009RetrospectiveSA,
  title={Retrospective safety analysis of atomoxetine in adult ADHD patients with or without comorbid alcohol abuse and dependence.},
  author={Lenard A. Adler and Timothy E Wilens and Shuyu Zhang and Todd M. Durell and Daniel Walker and Leslie M. Schuh and Ling Jin and Peter Feldman and Paula T. Trzepacz},
  journal={The American journal on addictions},
  year={2009},
  volume={18 5},
  pages={393-401}
}
This post hoc analysis compared the safety of atomoxetine treatment of ADHD in adults with or without comorbid alcohol abuse/dependence. Study completion rates in patients receiving atomoxetine were comparable between heavy drinkers (60.9%) and patients with no alcohol-use disorder (71.0%) but lower in nonheavy drinkers (35.7%); however, there was no significant difference in discontinuation rates due to adverse events or lack of efficacy among these groups. Alcohol-use disorder patients… CONTINUE READING

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