Retrospective exposure data for baby and children care products: an analysis of 48 clinical studies.

Abstract

To conduct a reliable safety assessment, accurate exposure information for cosmetic products and ingredients is needed. The aim of the present retrospective study was to determine the amount per application and the daily exposure for some of the most commonly used baby cosmetic products. Consumption data from 48 clinical studies performed on 1481 babies and children (from 0 to 10 years old) were reviewed and used to conduct a probabilistic evaluation of dermal exposure. Six categories of products were reviewed: rinseoff products for hair and body; rinse-off products for the whole body; leave-on products for face and body; cleansers for face and body; diaper dermatitis treatment products; shampoos. Subjects were provided with products and recorded detailed daily usage information over a 1-4-week period, depending on the study. Products were weighed at the start and upon completion of each study in order to determine the total amount of product used. The mean, median, standard deviation and 95th percentile were calculated for daily consumption and exposure, for several age groups from 0 to 10 years old. This study provides current baby cosmetic exposure information for commonly used products which will be useful for risk assessment purposes.

DOI: 10.1016/j.fct.2013.03.030
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@article{GomezBerrada2013RetrospectiveED, title={Retrospective exposure data for baby and children care products: an analysis of 48 clinical studies.}, author={Marie-Pierre Gomez-Berrada and Florian Gautier and D. Parent-Massin and P J Ferret}, journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association}, year={2013}, volume={57}, pages={185-94} }