Retrospective comparison of triple-sequence therapies in metastatic renal cell carcinoma.

@article{Busch2013RetrospectiveCO,
  title={Retrospective comparison of triple-sequence therapies in metastatic renal cell carcinoma.},
  author={Jonas Felix Busch and Christoph Seidel and Barbara Erber and Ahi Sema Issever and Stefan Hinz and Carsten Kempkensteffen and Ahmed Magheli and Kurt Miller and Viktor Gr{\"u}nwald and Steffen Weikert},
  journal={European urology},
  year={2013},
  volume={64 1},
  pages={62-70}
}
BACKGROUND The optimal sequence of targeted therapy in patients with metastatic renal cell carcinoma (mRCC) has not been defined. OBJECTIVE To describe the efficacy and toxicity of the most common sequences of targeted therapy, namely, receptor tyrosine kinase inhibitor (rTKI) and mammalian target of rapamycin inhibitor (mTORi), in different sequences after failure of vascular endothelial growth factor signaling inhibition (VEGFi) in first-line therapy. DESIGN, SETTING AND PARTICIPANTS… CONTINUE READING