Retrograde signaling in the development and modification of synapses.

@article{Fitzsimonds1998RetrogradeSI,
  title={Retrograde signaling in the development and modification of synapses.},
  author={R. M. Fitzsimonds and M. Poo},
  journal={Physiological reviews},
  year={1998},
  volume={78 1},
  pages={
          143-70
        }
}
  • R. M. Fitzsimonds, M. Poo
  • Published 1998
  • Medicine, Biology
  • Physiological reviews
  • Retrograde signaling from the postsynaptic cell to the presynaptic neuron is essential for the development, maintenance, and activity-dependent modification of synaptic connections. This review covers various forms of retrograde interactions at developing and mature synapses. First, we discuss evidence for early retrograde inductive events during synaptogenesis and how maturation of presynaptic structure and function is affected by signals from the postsynaptic cell. Second, we review the… CONTINUE READING

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