Retrograde but not anterograde bead movement in intact axons requires dynein.

@article{Wang1995RetrogradeBN,
  title={Retrograde but not anterograde bead movement in intact axons requires dynein.},
  author={Caihua Wang and David J. Asai and Kenneth R. Robinson},
  journal={Journal of neurobiology},
  year={1995},
  volume={27 2},
  pages={216-26}
}
Dynein and kinesin have been implicated as the molecular motors that are responsible for the fast transport of axonal membranous organelles and vesicles. Experiments performed in vitro with partially reconstituted preparations have led to the hypothesis that kinesin moves organelles in the anterograde direction and dynein moves them in the retrograde direction. However, the molecular basis of transport directionality remains unclear. In the experiments described here, carboxylated fluorescent… CONTINUE READING

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