Retrograde axonal transport obstruction of brain-derived neurotrophic factor (BDNF) and its TrkB receptor in the retina and optic nerve of American Cocker Spaniel dogs with spontaneous glaucoma.

@article{Iwabe2007RetrogradeAT,
  title={Retrograde axonal transport obstruction of brain-derived neurotrophic factor (BDNF) and its TrkB receptor in the retina and optic nerve of American Cocker Spaniel dogs with spontaneous glaucoma.},
  author={Simone Iwabe and Norma Moreno-Mendoza and Francisco J. Trigo-Tavera and Cheryl Crowder and Gustavo Adolfo Garc{\'i}a-S{\'a}nchez},
  journal={Veterinary ophthalmology},
  year={2007},
  volume={10 Suppl 1},
  pages={12-9}
}
OBJECTIVE To determine the degree of retrograde optic nerve axonal transport obstruction at the scleral lamina cribosa level by examining levels of brain-derived neurotrophic factor (BDNF) and its tyrosine kinase receptor type B (TrkB) in dogs presenting with high intraocular pressure. ANIMALS STUDIED A total of 10 eyes, four normal and six glaucomatous eyes, from normal and affected American Cocker Spaniels with primary glaucoma were studied. All eyes were assessed by neuro-ophthalmic… CONTINUE READING

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