Retrograde axonal and transsynaptic transport of macromolecules: Physiological and pathophysiological importance

@article{Schwab1977RetrogradeAA,
  title={Retrograde axonal and transsynaptic transport of macromolecules: Physiological and pathophysiological importance},
  author={Martin E. Schwab and Hans Thoenen},
  journal={Agents and Actions},
  year={1977},
  volume={7},
  pages={361-368}
}
Anterograde and retrograde transport within axons and dendrites of nerve cells represent an integral part of the nerve cell function and biochemistry. A few exogenous macromolecules with most different molecular weights and physico-chemical properties (Nerve Growth Factor, tetanus toxin, cholera toxin, various lectins, antibodies against dopamine-β-hydroxylase) have been shown to be taken up and transported with the retrograde axonal transport in exceedingly high amounts if compared to most… CONTINUE READING
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