Retrograde Control of Neural Circuit Formation

@article{Deppmann2006RetrogradeCO,
  title={Retrograde Control of Neural Circuit Formation},
  author={Christopher D Deppmann and David D Ginty},
  journal={Cell},
  year={2006},
  volume={127},
  pages={1306-1307}
}
Glial-derived neurotrophic factor (GDNF), secreted by skeletal muscle, triggers expression of the ETS transcription factor Pea3 in a subset of motor neurons in the spinal cord. In this issue, find that this retrograde GDNF-Pea3 signal controls dendrite patterning and assembly of a sensory-motor reflex circuit.