Retrogenesis: clinical, physiologic, and pathologic mechanisms in brain aging, Alzheimer’s and other dementing processes

@article{Reisberg1999RetrogenesisCP,
  title={Retrogenesis: clinical, physiologic, and pathologic mechanisms in brain aging, Alzheimer’s and other dementing processes},
  author={B. Reisberg and E. Franssen and S. M. Hasan and I. Monteiro and I. Boksay and Liduin E. M. Souren and S. Kenowsky and S. Auer and S. Elahi and A. Kluger},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
  year={1999},
  volume={249},
  pages={S28-S36}
}
Abstract Data from clinical, electrophysiologic, neurophysiologic, neuroimaging and neuropathologic sources indicates that the progression of brain aging and Alzheimer’s disease (AD) deterioration proceeds inversely to human ontogenic acquisition patterns. A word for this process of degenerative developmental recapitulation, “retrogenesis”, has been proposed. These retrogenic processes provide new insights into the pathologic mechanism of AD deterioration. An understanding of retrogenic… Expand
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