Retrogenesis: clinical, physiologic, and pathologic mechanisms in brain aging, Alzheimer’s and other dementing processes
@article{Reisberg1999RetrogenesisCP, title={Retrogenesis: clinical, physiologic, and pathologic mechanisms in brain aging, Alzheimer’s and other dementing processes}, author={Barry Reisberg and Emile H. Franssen and Syed Mahmood Hasan and Isabel Monteiro and Istvan Boksay and Lidu{\"i}n E.M. Souren and Sunnie Kenowsky and Stefanie R. Auer and Shahid Elahi and Alan Kluger}, journal={European Archives of Psychiatry and Clinical Neuroscience}, year={1999}, volume={249}, pages={S28-S36} }
Abstract Data from clinical, electrophysiologic, neurophysiologic, neuroimaging and neuropathologic sources indicates that the progression of brain aging and Alzheimer’s disease (AD) deterioration proceeds inversely to human ontogenic acquisition patterns. A word for this process of degenerative developmental recapitulation, “retrogenesis”, has been proposed. These retrogenic processes provide new insights into the pathologic mechanism of AD deterioration. An understanding of retrogenic…
163 Citations
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