Retro-metal-ene versus retro-Aldol: mechanistic insight into Rh-catalysed formal [3+2] cycloaddition.

  title={Retro-metal-ene versus retro-Aldol: mechanistic insight into Rh-catalysed formal [3+2] cycloaddition.},
  author={Song Liu and Tao Zhang and Lei Zhu and Kangbao Zhong and Jianxian Gong and Zhen Yang and Ruopeng Bai and Yu Lan},
  journal={Chemical communications},
  volume={54 96},
Theoretical calculations have been performed to investigate the mechanism and stereoselectivity of rhodium-catalysed intramolecular [3+2] cycloaddition for construction of a substituted hexahydropentalene complex. A new C-C bond cleavage mechanism, retro-Aldol-type, is proposed and verified for this Rh-catalysed [3+2] cycloaddition reaction. 
4 Citations



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