Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life.

@article{Sapieha2010RetinopathyOP,
  title={Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life.},
  author={Przemyslaw Sapieha and Jean-Sebastien Joyal and Jos{\'e} Carlos Rivera and Elsa Kermorvant-Duchemin and Florian Sennlaub and Pierre Hardy and Pierre Lachapelle and Sylvain Chemtob},
  journal={The Journal of clinical investigation},
  year={2010},
  volume={120 9},
  pages={3022-32}
}
Retinopathy of prematurity (ROP) is a major complication of preterm birth. It encompasses a spectrum of pathologies that affect vision, from mild disease that resolves spontaneously to severe disease that causes retinal detachment and subsequent blindness. The pathologies are characterized by an arrest in normal retinal vascular development associated with microvascular degeneration. The resulting ischemia and retinal hypoxia lead to excessive abnormal compensatory blood vessel growth. However… CONTINUE READING