Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.

@article{Gooyer2006RetinopathyIR,
  title={Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration.},
  author={Tanyth E de Gooyer and Kathryn A Stevenson and Pete Humphries and David A Simpson and Tom A. Gardiner and Alan W. Stitt},
  journal={Investigative ophthalmology & visual science},
  year={2006},
  volume={47 12},
  pages={5561-8}
}
PURPOSE Diabetic patients who also have retinitis pigmentosa (RP) appear to have fewer and less severe retinal microvascular lesions. Diabetic retinopathy may be linked to increased inner retinal hypoxia, with the possibility that this is exacerbated by oxygen usage during the dark-adaptation response. Therefore, patients with RP with depleted rod photoreceptors may encounter proportionately less retinal hypoxia, and, when diabetes is also present, there may be fewer retinopathic lesions. This… CONTINUE READING
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