Retinol forms retinoic acid via retinal.

  title={Retinol forms retinoic acid via retinal.},
  author={Chung Il Kim and Maria Anna Leo and Charles S. Lieber},
  journal={Archives of biochemistry and biophysics},
  volume={294 2},
Hepatic cytosol from normal deermice having cytosolic alcohol dehydrogenase (ADH+) also displays retinol dehydrogenase activity and converts retinol to retinoic acid, whereas cytosol from ADH- deermice lacks these enzyme activities and does not produce retinoic acid. Furthermore, microsomes from either strain do not convert retinol to retinoic acid. However, when cytosol from ADH- animals is added to the microsomes, retinoic acid is produced. The obligatory role of retinal as an intermediary… CONTINUE READING

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