Retinoids induce stem cell differentiation via epigenetic changes.


Vitamin A (all-trans retinol) and its active metabolites, collectively called retinoids, exert potent effects on stem cell differentiation and thus, the formation of the entire organism, in part via the modulation of the epigenome. All-trans retinoic acid (RA), through binding to the retinoic acid receptors (RARs), alters interactions of the RARs with… (More)
DOI: 10.1016/j.semcdb.2013.08.002

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