Retinoids induce lumen morphogenesis

Abstract

The development of most glandular organs begins with the invagination of an existing epithelial sheet into the underlying mesenchyme. The primary bud thus generated subsequently undergoes a series of morphogenetic events that culminate in the formation of branching tubes (excretory ducts) and hollow spheres (follicles, alveoli or acini). A crucial step in… (More)

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