Retinoids in embryonal development.

@article{Ross2000RetinoidsIE,
  title={Retinoids in embryonal development.},
  author={S A Ross and Peter McCaffery and U C Drager and Luigi M De Luca},
  journal={Physiological reviews},
  year={2000},
  volume={80 3},
  pages={1021-54}
}
The key role of vitamin A in embryonal development is reviewed. Special emphasis is given to the physiological action of retinoids, as evident from the retinoid ligand knockout models. Retinoid metabolism in embryonic tissues and teratogenic consequences of retinoid administration at high doses are presented. Physiological and pharmacological actions of retinoids are outlined and explained on the basis of their interactions as ligands of the nuclear retinoid receptors. Immediate target genes… CONTINUE READING
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Differential distribution of retinoic acid synthesis in the chicken embryo as determined by immunolocalization of the retinoic acid synthetic enzyme, RALDH-2

K BERGGREN, P MCCAFFERY, U DRAGER, CJ. FOREHAND
Dev Biol • 1999
View 15 Excerpts
Highly Influenced

of normal cardiovascular development in the vitamin A-deprived quail embryo by natural retinoids

H DERSCH, ZILE MH. Inductio
Dev Biol 160: 424–433, • 1993
View 4 Excerpts
Highly Influenced

Retinoid-binding proteins in craniofacial development.

Journal of craniofacial genetics and developmental biology • 1991
View 5 Excerpts
Highly Influenced

acid and teratocarcinoma

GUDAS LJ. Retinoi
Semin Dev Biol 2: 171–179, • 1991
View 4 Excerpts
Highly Influenced

and their receptors in differentiation, embryogenesis, and neoplasia

DE LUCA LM. Retinoid
FASEB J 5: 2924–2933, • 1991
View 4 Excerpts
Highly Influenced

of congenital abnormalities by vitamin A

AE CZEIZEL, ROCKENBAUER M. Preventio
Int J Vitam Nutr Res 68: 219–231, • 1998
View 3 Excerpts
Highly Influenced

Novel retinoic acid receptor ligands in Xenopus embryos.

Proceedings of the National Academy of Sciences of the United States of America • 1996
View 11 Excerpts
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