Retinoids and apoptosis: implications for cancer chemoprevention and therapy.

@article{Lotan1995RetinoidsAA,
  title={Retinoids and apoptosis: implications for cancer chemoprevention and therapy.},
  author={Reuben Lotan},
  journal={Journal of the National Cancer Institute},
  year={1995},
  volume={87 22},
  pages={
          1655-7
        }
}
Lung cancer in the United States leads other cancers in both incidence and mortality (1). The severe morbidity of lung cancer and the discouraging 15% overall 5-year survival rate have not improved despite advancements in treatment modalities. Furthermore, the incidence of lung cancer among women is increasing. Therefore, novel approaches to control this dreadful disease are urgently needed. Biological agents such as differentiati oninducing agents are being evaluated in clinical trials for… CONTINUE READING

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