Retinoids: new insight into smooth muscle cell growth inhibition.

  title={Retinoids: new insight into smooth muscle cell growth inhibition.},
  author={Joseph M. Miano and Bradford C. Berk},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={21 5},
The successful management of vascular occlusive diseases, particularly those due to procedural interventions for preexisting atherosclerosis, will likely require the targeting of numerous cellular processes rather than any 1 gene, protein, or signaling pathway. This fact is underscored by the failure of virtually all clinical trials employing pathwayor factor-specific therapeutics to limit restenosis after percutaneous vascular interventions. Retinoids are natural and synthetic derivatives of… CONTINUE READING


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