Retinoid metabolism is altered in human and mouse cicatricial alopecia

Abstract

C57BL/6 mice develop dermatitis and scarring alopecia resembling human cicatricial alopecias (CAs), particularly the central centrifugal CA (CCCA) type. To evaluate the role of retinoids in CA, the expression of retinoid metabolism components were examined in these mice with mild, moderate, or severe CA compared with hair cycle-matched mice with no disease… (More)
DOI: 10.1038/jid.2012.393

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