Retinoid-binding protein distribution in the developing mammalian nervous system.

  title={Retinoid-binding protein distribution in the developing mammalian nervous system.},
  author={Malcolm Maden and David E. Ong and Frank Chytil},
  volume={109 1},
We have analysed the distribution of cellular retinol-binding protein (CRBP) and cellular retinoic acid-binding protein (CRABP) in the day 8.5-day 12 mouse and rat embryo. CRBP is localised in the heart, gut epithelium, notochord, otic vesicle, sympathetic ganglia, lamina terminalis of the brain, and, most strikingly, in a ventral stripe across the developing neural tube in the future motor neuron region. This immunoreactivity remains in motor neurons and, at later stages, motor axons are… CONTINUE READING
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