Retinoid X receptor γ up-regulation is correlated with dedifferentiation of tumor cells and lymph node metastasis in papillary thyroid carcinoma.

@article{Liu2011RetinoidXR,
  title={Retinoid X receptor γ up-regulation is correlated with dedifferentiation of tumor cells and lymph node metastasis in papillary thyroid carcinoma.},
  author={Zhiyan Liu and Geng-yin Zhou and Misa Nakamura and Yanhua Bai and Yaqiong Li and Takashi Ozaki and Ichiro Mori and Akira Miyauchi and Kennichi Kakudo},
  journal={Pathology international},
  year={2011},
  volume={61 3},
  pages={109-15}
}
The expression of retinoid X receptor γ (RXRγ) and the clinicopathological parameters of total 69 patients with papillary thyroid carcinoma (PTC) larger than 1 cm were examined. The PTCs were classified into two groups according to the presence of loss of cellular polarity/cohesiveness (LOP/C). The expression of RXRγ mRNA was examined by reverse transcriptase polymerase chain reaction and quantitative real-time PCR. The RXRγ mRNA up-regulation was found to be positively correlated with… CONTINUE READING