Retinoic acid signaling pathways in development and diseases.

Abstract

Retinoids comprise a group of compounds each composed of three basic parts: a trimethylated cyclohexene ring that is a bulky hydrophobic group, a conjugated tetraene side chain that functions as a linker unit, and a polar carbon-oxygen functional group. Biochemical conversion of carotenoid or other retinoids to retinoic acid (RA) is essential for normal… (More)
DOI: 10.1016/j.bmc.2013.11.025

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