Retinoic acid receptors beta and gamma do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand.

@article{Hauksdttir2003RetinoicAR,
  title={Retinoic acid receptors beta and gamma do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand.},
  author={Herborg Hauksd{\'o}ttir and Behnom Farboud and Martin L. Privalsky},
  journal={Molecular endocrinology},
  year={2003},
  volume={17 3},
  pages={373-85}
}
Retinoic acid receptors (RARs) are important mediators of retinoid signaling in morphogenesis, development, and cell differentiation. Three major isotypes of RARs, denoted alpha, beta, and gamma, have been identified, each encoded by a distinct genetic locus. Although RARalpha, RARbeta, and RARgamma share many structural and functional features, these three isotypes are known to play unique, as well as overlapping, roles in physiology and development. We report here that the three RAR isotypes… CONTINUE READING

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