Retinoic acid receptor and retinoid X receptor subtype expression for the differential diagnosis of thyroid neoplasms.

@article{Hoftijzer2009RetinoicAR,
  title={Retinoic acid receptor and retinoid X receptor subtype expression for the differential diagnosis of thyroid neoplasms.},
  author={Hendrieke C Hoftijzer and Ying Ying Liu and Hans Morreau and Ton van Wezel and Alberto Martin Pereira and Eleonora P. M. Corssmit and Johannes Anthonius Romijn and Jan Smit},
  journal={European journal of endocrinology},
  year={2009},
  volume={160 4},
  pages={631-8}
}
BACKGROUND Although differential expression of retinoic acid receptor (RAR) subtypes between benign and malignant thyroid tissues has been described, their diagnostic value has not been reported. AIM To investigate the diagnostic accuracy of RAR and retinoid X receptor (RXR) subtype protein expression for the differential diagnosis of thyroid neoplasms. METHODS We used a tissue array containing 93 benign thyroid tissues (normal thyroid, multinodular goiter, and follicular adenoma (FA)) and… CONTINUE READING