Retinoic acid posttranscriptionally up-regulates proteolipid protein gene expression in C6 glioma cells.

Abstract

The proteolipid protein (PLP) gene codes for the major central nervous system myelin protein. We have studied the effects of different agents on the expression of the PLP gene in C6 glioma cells. Retinoic acid (RA), but not dexamethasone, estradiol, insulin, growth hormone, or vitamin D3, had a drastic effect, increasing 10-20-fold the level of PLP mRNA… (More)

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Cite this paper

@article{LpezBarahona1993RetinoicAP, title={Retinoic acid posttranscriptionally up-regulates proteolipid protein gene expression in C6 glioma cells.}, author={M{\'o}nica L{\'o}pez-Barahona and Meritxell Mi{\~n}ano and Emilia Mira and Teresa Iglesias and Henk Stunnenberg and Angeles Rodr{\'i}guez-Pe{\~n}a and J. J. Bernal and A. Mu{\~n}oz}, journal={The Journal of biological chemistry}, year={1993}, volume={268 34}, pages={25617-23} }