Retinoic acid-inducible gene-I (RIG-I) is induced by IFN-{gamma} in human mesangial cells in culture: possible involvement of RIG-I in the inflammation in lupus nephritis.

Abstract

Interferon-gamma is a potent Th1-type cytokine and a key molecule in the pathogenesis of autoimmune diseases including lupus nephritis. Retinoic acid-inducible gene-I is a putative RNA helicase that plays an important role in immune and inflammatory reactions. We previously demonstrated the increased expression of the retinoic acid-inducible gene-I protein… (More)
DOI: 10.1177/0961203309360540

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@article{Imaizumi2010RetinoicAG, title={Retinoic acid-inducible gene-I (RIG-I) is induced by IFN-\{gamma\} in human mesangial cells in culture: possible involvement of RIG-I in the inflammation in lupus nephritis.}, author={Tadaatsu Imaizumi and H. Tanaka and Atsushi Tajima and Kaya Tsuruga and Eiji Oki and Hiroshi Sashinami and Takahiro Matsumiya and H. Yoshida and Itsuro Inoue and E. Ito}, journal={Lupus}, year={2010}, volume={19 7}, pages={830-6} }