Retinoic acid increases the effect of bone morphogenetic protein type 2 on osteogenic differentiation of human adipose-derived stem cells

@inproceedings{Cruz2019RetinoicAI,
  title={Retinoic acid increases the effect of bone morphogenetic protein type 2 on osteogenic differentiation of human adipose-derived stem cells},
  author={Ariadne Cristiane Cabral Cruz and Francielle Tramontini Gomes de Souza Cardozo and Ricardo de Souza Magini and Cl{\'a}udia Maria Oliveira Sim{\~o}es},
  booktitle={Journal of applied oral science : revista FOB},
  year={2019}
}
BACKGROUND Bone morphogenetic protein type 2 (BMP-2) and retinoic acid (RA) are osteoinductive factors that stimulate endogenous mechanisms of bone repair which can be applied on management of osseous defects in oral and maxillofacial fields. OBJECTIVE Considering the different results of RA on osteogenesis and its possible use to substitute/potency BMP-2 effects, this study evaluated the outcomes of BMP-2, RA, and BMP-2+RA treatments on in vitro osteogenic differentiation of human adipose… CONTINUE READING

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