Retinoic acid effects on endothelial cell function: interaction with interleukin 1.

@article{SpencerGreen1994RetinoicAE,
  title={Retinoic acid effects on endothelial cell function: interaction with interleukin 1.},
  author={George T Spencer-Green},
  journal={Clinical immunology and immunopathology},
  year={1994},
  volume={72 1},
  pages={
          53-61
        }
}
  • G. Spencer-Green
  • Published 1 July 1994
  • Biology, Medicine
  • Clinical immunology and immunopathology
Blood vessel angiogenesis is an important component of chronic synovitis, and its regulation may be mediated through local production and effects of certain inflammatory cytokines, including interleukin-1 (IL-1). Retinoic acid (RA) can alter the progression of some inflammatory arthritic diseases, presumably through effects on fibroblast collagenase and PGE2 production. To explore alternate hypotheses, we examined the interaction of retinoic acid and IL-1 on endothelial cell (EC) function and… 
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