Retinoic acid causes an anteroposterior transformation in the developing central nervous system.

Abstract

All-trans retinoic acid (RA) is well known as a biologically active form of vitamin A and a teratogen. The identification of nuclear receptors for this ligand suggests strongly that it is an endogenous signal molecule, and measurements of RA and teratogenic manipulations suggest further that RA is a morphogen specifying the anteroposterior axis during limb… (More)

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Cite this paper

@article{Durston1989RetinoicAC, title={Retinoic acid causes an anteroposterior transformation in the developing central nervous system.}, author={Antony J Durston and J-M. Timmermans and W. J. Hage and Henri{\"e}tte Hendriks and Nannes De Vries and M Heideveld and Pieter Dirk Nieuwkoop}, journal={Nature}, year={1989}, volume={340 6229}, pages={140-4} }