Retinoic acid: its biosynthesis and metabolism.

@article{Napoli1999RetinoicAI,
  title={Retinoic acid: its biosynthesis and metabolism.},
  author={Joseph L Napoli},
  journal={Progress in nucleic acid research and molecular biology},
  year={1999},
  volume={63},
  pages={139-88}
}
  • Joseph L Napoli
  • Published 1999 in
    Progress in nucleic acid research and molecular…
This article presents a model that integrates the functions of retinoid-binding proteins with retinoid metabolism. One of these proteins, the widely expressed (throughout retinoid target tissues and in all vertebrates) and highly conserved cellular retinol-binding protein (CRBP), sequesters retinol in an internal binding pocket that segregates it from the intracellular milieu. The CRBP-retinol complex appears to be the quantitatively major form of retinol in vivo, and may protect the… CONTINUE READING

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Diverse Functions of Retinoic Acid in Brain Vascular Development.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2016
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