Retinal vessel abnormalities of phototoxic retinopathy in rats.

  title={Retinal vessel abnormalities of phototoxic retinopathy in rats.},
  author={Roy W. Bellhorn and Margaret S. Burns and J V Benjamin},
  journal={Investigative ophthalmology & visual science},
  volume={19 6},
Phototoxic retinopathy in rats is characterized by a progressive loss of the outer retinal layers. During the neural degenerative phases, a sequence of vascular change occurs. Whole mounts of ink-injected retinal vessels and flat mounts of trypsin-digested retinal vessels show areas of capillary nonperfusion and acellularity and enlargement of retinal capillaries in the deep bed. When the photoreceptor and outer nuclear layers have disappeared, portions of the remaining deep capillary bed… CONTINUE READING