Retinal vascular endothelial cell endocytosis increases in early diabetes.

@article{Gardiner1995RetinalVE,
  title={Retinal vascular endothelial cell endocytosis increases in early diabetes.},
  author={Tom A. Gardiner and Alan W. Stitt and Desmond B. Archer},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1995},
  volume={72 4},
  pages={439-44}
}
BACKGROUND Several physiological studies in recent years have convincingly demonstrated increased clearance of intravascular protein tracers by several different tissues, including the retina, during early diabetes and galactosemia in the rat. This change has been described as a consequence of increased permeation, although vascular leakage has not been demonstrated, and the fate of such tracers remains unelucidated. EXPERIMENTAL DESIGN A pilot study in this laboratory showed no evidence of… CONTINUE READING