Retinal toxicity of intravitreal tissue plasminogen activator: case report and literature review.

@article{Chen2003RetinalTO,
  title={Retinal toxicity of intravitreal tissue plasminogen activator: case report and literature review.},
  author={San-Ni Chen and T Yang and C T Ho and Ya-Hui Kuo and Yeung Yip and An-Ning Chao},
  journal={Ophthalmology},
  year={2003},
  volume={110 4},
  pages={704-8}
}
OBJECTIVE To present the clinical picture of retinal toxicity of commercial tissue plasminogen activator (tPA). DESIGN Case report and literature review. METHODS Two successive intravitreal injections of tPA (50 micro g) 3 days apart with gas tamponade were given to treat a 49-year-old man with submacular hemorrhage. The adverse consequences of this… CONTINUE READING