• DOI:10.1038/nature05161
Corpus ID: 4415311

Retinal repair by transplantation of photoreceptor precursors

@article{MacLaren2006RetinalRB,
  title={Retinal repair by transplantation of photoreceptor precursors},
  author={R. MacLaren and R. A. Pearson and A. MacNeil and R. Douglas and T. Salt and M. Akimoto and A. Swaroop and J. Sowden and R. Ali},
  journal={Nature},
  year={2006},
  volume={444},
  pages={203-207}
}

• R. MacLaren, R. A. Pearson, +6 authors R. Ali
• Published 2006
• Biology, Medicine
• Nature

Photoreceptor loss causes irreversible blindness in many retinal diseases. Repair of such damage by cell transplantation is one of the most feasible types of central nervous system repair; photoreceptor degeneration initially leaves the inner retinal circuitry intact and new photoreceptors need only make single, short synaptic connections to contribute to the retinotopic map. So far, brain- and retina-derived stem cells transplanted into adult retina have shown little evidence of being able to… Expand

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