Retinal neuroprotection against ischemia-reperfusion damage induced by postconditioning.

@article{Fernandez2009RetinalNA,
  title={Retinal neuroprotection against ischemia-reperfusion damage induced by postconditioning.},
  author={Diego Carlos Fernandez and Melina P. Bordone and M{\'o}nica Silvia Chianelli and Ruth E Rosenstein},
  journal={Investigative ophthalmology & visual science},
  year={2009},
  volume={50 8},
  pages={3922-30}
}
PURPOSE Retinal ischemia may provoke blindness. There is no effective treatment against retinal ischemic damage. The authors investigated whether brief intermittent ischemia applied during the onset of reperfusion (i.e., postconditioning) protects the retina from ischemia-reperfusion damage. METHODS Ischemia was induced by increasing intraocular pressure (120 mm Hg for 40 or 60 minutes). Five minutes after reperfusion, animals underwent 3, 7, or 10 cycles of 1-minute ischemia/1-minute… CONTINUE READING
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