Retinal nerve fiber layer and future risk of multiple sclerosis.

@article{Costello2008RetinalNF,
  title={Retinal nerve fiber layer and future risk of multiple sclerosis.},
  author={Fiona E Costello and William Hodge and Y. I. Pan and Luanne Metz and Randy H. Kardon},
  journal={The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques},
  year={2008},
  volume={35 4},
  pages={482-7}
}
BACKGROUND Optical coherence tomography (OCT)--measured retinal nerve fiber layer (RNFL) values may represent a surrogate biomarker for axonal integrity in multiple sclerosis (MS). The purpose of this study was to determine whether RNFL measurements obtained within two years of an optic neuritis (ON) event distinguish patients at increased risk of developing clinically-definite MS (CDMS). METHODS Fifty consecutively sampled patients who experienced a single ON event were followed… CONTINUE READING
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