Retinal glutamate in diabetes and effect of antioxidants.

  title={Retinal glutamate in diabetes and effect of antioxidants.},
  author={Renu A Kowluru and Ronald L. Engerman and Gary L. Case and Timothy S Kern},
  journal={Neurochemistry international},
  volume={38 5},
Diabetes results in various biochemical abnormalities in the retina, but which of these abnormalities are critical in the development of retinopathy is not known. The aim of this study is to examine the effect of antioxidant supplementation on diabetes-induced alterations of retinal glutamate, and to explore the inter-relationship between alterations of retinal glutamate, oxidative stress, and nitric oxide (NO) in diabetes. Glutamate was measured in the retina at 2 months of diabetes in rats… CONTINUE READING


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