Retinal ganglion cells in Alzheimer's disease and aging.

@article{Curcio1993RetinalGC,
  title={Retinal ganglion cells in Alzheimer's disease and aging.},
  author={Christine A. Curcio and D N Drucker},
  journal={Annals of neurology},
  year={1993},
  volume={33 3},
  pages={248-57}
}
Optic nerve and retinal ganglion cell (GC) degeneration are possible explanations for the poor visual function reported in patients with Alzheimer's disease (AD). We investigated whether GC loss could be attributed to AD compared with control subjects by measuring the spatial density of GC (cells/mm2) with methods previously used to analyze the GC distribution of young normal retinas. Retinas from 4 autopsy-confirmed, severely demented patients with AD and 4 age- and sex-matched control… CONTINUE READING

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