Retinal ganglion cell death postponed: giving apoptosis a break?

  title={Retinal ganglion cell death postponed: giving apoptosis a break?},
  author={Lilian Kisiswa and Adrian G Dervan and Julie Albon and James E. Morgan and Michael A. Wride},
  journal={Ophthalmic research},
  volume={43 2},
Glaucoma is characterised by the preferential death of retinal ganglion cells (RGCs). However, mammalian models indicate that neurons pass through a period in which they manifest signs of neuronal damage, but have yet to fully commit to death. Mounting evidence suggests that one of the clearest indications of this process is the reduction in RGC dendritic arborisation, resulting in functional compromise. The extent to which this may be reversible is unclear, since the molecular events that… CONTINUE READING


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