Retinal ganglion cell and inner plexiform layer thinning in clinically isolated syndrome.

@article{Oberwahrenbrock2013RetinalGC,
  title={Retinal ganglion cell and inner plexiform layer thinning in clinically isolated syndrome.},
  author={Timm Oberwahrenbrock and Marius Ringelstein and Simon Jentschke and Katrin Deuschle and Katharina Klumbies and J Bellmann-Strobl and Jens Harmel and Klemens Ruprecht and Sven Schippling and H. Hartung and Orhan Aktas and Alexander Ulrich Brandt and Friedemann Paul},
  journal={Multiple sclerosis},
  year={2013},
  volume={19 14},
  pages={1887-95}
}
BACKGROUND Axonal and neuronal damage are widely accepted as key events in the disease course of multiple sclerosis. However, it has been unclear to date at which stage in disease evolution neurodegeneration begins and whether neuronal damage can occur even in the absence of acute inflammatory attacks. OBJECTIVE To characterize inner retinal layer changes in patients with clinically isolated syndrome (CIS). METHOD 45 patients with CIS and age- and sex-matched healthy controls were… CONTINUE READING

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