Retinal drug delivery using eyedrop preparations of poly-L-lysine-modified liposomes.


The purpose of this study was to develop surface-modified liposomes that enhance the efficiency of eye drop drug delivery to the retina. Various molecular weights and concentrations of the water-soluble cationic polymer poly-L-lysine (PLL) were used to modify the surface of submicronized (100 nm) liposomes. Physicochemical properties of surface-modified… (More)
DOI: 10.1016/j.ejpb.2012.10.014


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