Retinal degeneration and local oxygen metabolism.

  title={Retinal degeneration and local oxygen metabolism.},
  author={Dao-Yi Yu and Stephen J. Cringle},
  journal={Experimental eye research},
  volume={80 6},
Vision loss due to various forms of outer retinal degeneration remains a major problem in clinical ophthalmology. Most retinal degenerations are precipitated by genetic mutations affecting the retinal pigment epithelium and sensory retina, but it is becoming increasingly evident that resultant metabolic changes within the retina may also contribute to the further progression of photoreceptor cell loss. In particular, a role for the local oxygen environment within the retina has been proposed… CONTINUE READING
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