Retinal VEGF levels correlate with ocular circulation measured by a laser speckle-micro system in an oxygen-induced retinopathy rat model

@article{Matsumoto2017RetinalVL,
  title={Retinal VEGF levels correlate with ocular circulation measured by a laser speckle-micro system in an oxygen-induced retinopathy rat model},
  author={Tadashi Matsumoto and Yuta Saito and Takashi Itokawa and Tomoaki Shiba and Mari Saito Oba and Haruo Takahashi and Yuichi Hori},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2017},
  volume={255},
  pages={1981-1990}
}
We used a Laser speckle flowgraphy (LSFG)-micro system to examine the relationship between ocular blood flow and retinal vascular endothelial growth factor (VEGF) at retinopathy onset in oxygen-induced ischemic retinopathy (OIR) model rats. Sixteen 50/10 OIR rats were compared with 17 control rats reared in room air. In postnatal day 14 (P14) and P18 rats, we measured and analyzed the left eye’s mean blur rate (MBR) by setting a rubber band on the optic nerve head center, using the LSFG-Micro… CONTINUE READING