Retinal ON bipolar cells express a new PCP2 splice variant that accelerates the light response.

@article{Xu2008RetinalOB,
  title={Retinal ON bipolar cells express a new PCP2 splice variant that accelerates the light response.},
  author={Ying Xu and Pyroja Sulaiman and Rod M. Feddersen and Jian Liu and Robert G. Smith and Noga Vardi},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2008},
  volume={28 36},
  pages={8873-84}
}
PCP2, a member of the GoLoco domain-containing family, is present exclusively in cerebellar Purkinje cells and retinal ON bipolar cells. Its function in these tissues is unknown. Biochemical and expression system studies suggest that PCP2 is a guanine nucleotide dissociation inhibitor, although a guanine nucleotide exchange factor has also been suggested. Here, we studied the function of PCP2 in ON bipolar cells because their light response depends on Galpha(o1), which is known to interact with… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 83 references

Similar Papers

Loading similar papers…